ICS 13.020 CCS CAQI Z 04 团体 标准 T/CAQI 258—2022 化工园区化学品人体健康风险评估技术指南 Technical guidelines for human health risk assessment of chemicals in chemical industry parks 2022 - 04 - 01发布 2022 - 07 - 01实施 中国质量检验协会 发布 全国团体标准信息平台 T/CAQI 258 —2022 I 目次 前言 ................................ ................................ ................................ ................................ ................................ ...... II 1 范围 ................................ ................................ ................................ ................................ ................................ .. 1 2 规范性引用文件 ................................ ................................ ................................ ................................ .............. 1 3 术语和定义 ................................ ................................ ................................ ................................ ...................... 1 4 工作程序 ................................ ................................ ................................ ................................ .......................... 2 5 数据收集 ................................ ................................ ................................ ................................ .......................... 3 5.1 化工园区化学品固有性质收集 ................................ ................................ ................................ ............... 3 5.2 化工园区化学品暴露参数收集 ................................ ................................ ................................ ............... 3 6 危害识别 ................................ ................................ ................................ ................................ .......................... 3 6.1 化学品的暴露人群确认 ................................ ................................ ................................ ........................... 3 6.2 化学品的空间分布确认 ................................ ................................ ................................ ........................... 3 6.3 化学品的不良效应确认 ................................ ................................ ................................ ........................... 3 7 暴露评估 ................................ ................................ ................................ ................................ .......................... 4 7.1 暴露情景确认 ................................ ................................ ................................ ................................ ........... 4 7.2 职业暴露量计算 ................................ ................................ ................................ ................................ ....... 4 7.3 环境间接暴露 量计算 ................................ ................................ ................................ ............................... 4 7.4 消费者暴露量计算 ................................ ................................ ................................ ................................ ... 6 8 剂量 -效应评估 ................................ ................................ ................................ ................................ ................ 8 9 风险表征 ................................ ................................ ................................ ................................ .......................... 9 附录 A（资料性） 不同不良效应危害识别推荐方法 ................................ ................................ .................. 10 附录 B（资料性） 暴露评估方法及默认参数 ................................ ................................ ............................... 11 B.1 职业人群 皮肤接触暴露评估推荐方法模型及参数 ................................ ................................ ............. 11 B.2 化工园区周边人群暴露评估推荐方法模型及参数 ................................ ................................ ............. 11 附录 C（资料性） 不良效应外推至人体的不确定性参数 ................................ ................................ ........... 13 全国团体标准信息平台 T/CAQI 258 —2022 II 前言 本文件按照 GB/T 1.1 —2020《标准化工作导则